Improved Specificity and Safety of Anti-Hepatitis B Virus TALENs Using Obligate Heterodimeric FokI Nuclease Domains

Persistent hepatitis B virus (HBV) infection remains a serious medical problem worldwide, with an estimated global burden of 257 million carriers. Prophylactic and therapeutic interventions, in the form of a vaccine, immunomodulators, and nucleotide and nucleoside analogs, are available. Vaccination...

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Detalles Bibliográficos
Autores principales: Smith, Tiffany, Singh, Prashika, Chmielewski, Kay Ole, Bloom, Kristie, Cathomen, Toni, Arbuthnot, Patrick, Ely, Abdullah
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8310341/
https://www.ncbi.nlm.nih.gov/pubmed/34372550
http://dx.doi.org/10.3390/v13071344

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8310341/
https://www.ncbi.nlm.nih.gov/pubmed/34372550
http://dx.doi.org/10.3390/v13071344

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