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In vitro cellular and proteome assays identify Wnt pathway and CDKN2A-regulated senescence affected in mesenchymal stem cells from mice after a chronic LD gamma irradiation in utero

Reliable data on the effects of chronic prenatal exposure to low dose (LD) of ionizing radiation in humans are missing. There are concerns about adverse long-term effects that may persist throughout postnatal life of the offspring. Due to their slow cell cycle kinetics and life-long residence time i...

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Detalles Bibliográficos
Autores principales: Schuster, Martina, Tewary, Gargi, Bao, Xuanwen, Subedi, Prabal, Hauck, Stefanie M., Olsen, Ann Karin, Eide, Dag Markus, Trott, Klaus Rüdiger, Götz, Sebastian, Atkinson, Michael J., Rosemann, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8310520/
https://www.ncbi.nlm.nih.gov/pubmed/34287697
http://dx.doi.org/10.1007/s00411-021-00925-7