Cystine transporter SLC7A11/xCT in cancer: ferroptosis, nutrient dependency, and cancer therapy

The cystine/glutamate antiporter SLC7A11 (also commonly known as xCT) functions to import cystine for glutathione biosynthesis and antioxidant defense and is overexpressed in multiple human cancers. Recent studies revealed that SLC7A11 overexpression promotes tumor growth partly through suppressing...

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Detalles Bibliográficos
Autores principales: Koppula, Pranavi, Zhuang, Li, Gan, Boyi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Higher Education Press 2020
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8310547/
https://www.ncbi.nlm.nih.gov/pubmed/33000412
http://dx.doi.org/10.1007/s13238-020-00789-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8310547/
https://www.ncbi.nlm.nih.gov/pubmed/33000412
http://dx.doi.org/10.1007/s13238-020-00789-5

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