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Targeting of adipose tissue macrophages by bee venom phospholipase A2 attenuates high-fat diet-induced obesity

BACKGROUND/OBJECTIVES: Adipose tissue macrophages (ATMs) exist in either the M1 or M2 form. The anti-inflammatory M2 ATMs accumulate in lean individuals, whereas the pro-inflammatory M1 ATMs accumulate in obese individuals. Bee venom phospholipase A2 (bvPLA2), a major component in honeybee (Apis mel...

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Detalles Bibliográficos
Autores principales: Jeong, Hyunju, Lee, Chanju, Cheng, Chenyu, Chou, Hung Chun, Yang, HyeJin, Bae, Hyunsu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8310798/
https://www.ncbi.nlm.nih.gov/pubmed/33947969
http://dx.doi.org/10.1038/s41366-021-00823-4