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Decreased ATM Function Causes Delayed DNA Repair and Apoptosis in Common Variable Immunodeficiency Disorders

PURPOSE: Common variable immunodeficiency disorders (CVID) is characterized by low/absent serum immunoglobulins and susceptibility to bacterial infection. Patients can develop an infections-only phenotype or a complex disease course with inflammatory, autoimmune, and/or malignant complications. We h...

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Detalles Bibliográficos
Autores principales: Hargreaves, Chantal E., Salatino, Silvia, Sasson, Sarah C., Charlesworth, James E. G., Bateman, Elizabeth, Patel, Arzoo M., Anzilotti, Consuelo, Broxholme, John, Knight, Julian C., Patel, Smita Y.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8310859/
https://www.ncbi.nlm.nih.gov/pubmed/34009545
http://dx.doi.org/10.1007/s10875-021-01050-2