Cargando…
Decreased ATM Function Causes Delayed DNA Repair and Apoptosis in Common Variable Immunodeficiency Disorders
PURPOSE: Common variable immunodeficiency disorders (CVID) is characterized by low/absent serum immunoglobulins and susceptibility to bacterial infection. Patients can develop an infections-only phenotype or a complex disease course with inflammatory, autoimmune, and/or malignant complications. We h...
Autores principales: | Hargreaves, Chantal E., Salatino, Silvia, Sasson, Sarah C., Charlesworth, James E. G., Bateman, Elizabeth, Patel, Arzoo M., Anzilotti, Consuelo, Broxholme, John, Knight, Julian C., Patel, Smita Y. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer US
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8310859/ https://www.ncbi.nlm.nih.gov/pubmed/34009545 http://dx.doi.org/10.1007/s10875-021-01050-2 |
Ejemplares similares
-
Application of whole genome and RNA sequencing to investigate the genomic landscape of common variable immunodeficiency disorders
por: van Schouwenburg, Pauline A., et al.
Publicado: (2015) -
A homozygous variant disrupting the PIGH start‐codon is associated with developmental delay, epilepsy, and microcephaly
por: Pagnamenta, Alistair T., et al.
Publicado: (2018) -
Absence of ERK5/MAPK7 delays tumorigenesis in Atm(−/−) mice
por: Granados-Jaén, Alba, et al.
Publicado: (2016) -
A Decreased Frequency of Regulatory T Cells in Patients with Common Variable Immunodeficiency
por: Melo, Karina M., et al.
Publicado: (2009) -
ATM theory and application
por: McDysan, David E.
Publicado: (1995)