Cargando…
Molecular mechanisms of opioid tolerance: From opioid receptors to inflammatory mediators (Review)
Opioids are considered the most effective analgesics for the treatment of both acute and chronic pain. However, prolonged opioid use can induce a certain level of tolerance to its analgesic effects, leading to a reduction in its effectiveness, addiction and abuse. A better understanding of the mecha...
Autores principales: | , , , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
D.A. Spandidos
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8311239/ https://www.ncbi.nlm.nih.gov/pubmed/34345286 http://dx.doi.org/10.3892/etm.2021.10437 |