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ChaC glutathione specific γ-glutamylcyclotransferase 1 inhibits cell viability and increases the sensitivity of prostate cancer cells to docetaxel by inducing endoplasmic reticulum stress and ferroptosis

The present study aimed to determine the effects and mechanism of ChaC glutathione specific γ-glutamylcyclotransferase 1 (CHAC1) on cell viability and the sensitivity of prostate cancer cells to docetaxel. Compared with non-tumor human prostate epithelial RWPE-1 cells, the mRNA and protein levels of...

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Detalles Bibliográficos
Autores principales: He, Saifei, Zhang, Miao, Ye, Ying, Zhuang, Juhua, Ma, Xing, Song, Yanan, Xia, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8311285/
https://www.ncbi.nlm.nih.gov/pubmed/34345279
http://dx.doi.org/10.3892/etm.2021.10429