Mycobacterium tuberculosis Protein PE6 (Rv0335c), a Novel TLR4 Agonist, Evokes an Inflammatory Response and Modulates the Cell Death Pathways in Macrophages to Enhance Intracellular Survival

Mycobacterium tuberculosis (M. tb) is an intracellular pathogen that exploits moonlighting functions of its proteins to interfere with host cell functions. PE/PPE proteins utilize host inflammatory signaling and cell death pathways to promote pathogenesis. We report that M. tb PE6 protein (Rv0335c)...

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Detalles Bibliográficos
Autores principales: Sharma, Neha, Shariq, Mohd, Quadir, Neha, Singh, Jasdeep, Sheikh, Javaid A., Hasnain, Seyed E., Ehtesham, Nasreen Z.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8311496/
https://www.ncbi.nlm.nih.gov/pubmed/34322125
http://dx.doi.org/10.3389/fimmu.2021.696491

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8311496/
https://www.ncbi.nlm.nih.gov/pubmed/34322125
http://dx.doi.org/10.3389/fimmu.2021.696491

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