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A SGLT2 Inhibitor Dapagliflozin Alleviates Diabetic Cardiomyopathy by Suppressing High Glucose-Induced Oxidative Stress in vivo and in vitro

Diabetic cardiomyopathy (DCM) is a serious complication of diabetes mellitus (DM). One of the hallmarks of the DCM is enhanced oxidative stress in myocardium. The aim of this study was to research the underlying mechanisms involved in the effects of dapagliflozin (Dap) on myocardial oxidative stress...

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Detalles Bibliográficos
Autores principales: Xing, Yu-jie, Liu, Biao-hu, Wan, Shu-jun, Cheng, Yi, Zhou, Si-min, Sun, Yue, Yao, Xin-ming, Hua, Qiang, Meng, Xiang-jian, Cheng, Jin-han, Zhong, Min, Zhang, Yan, Lv, Kun, Kong, Xiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8311522/
https://www.ncbi.nlm.nih.gov/pubmed/34322029
http://dx.doi.org/10.3389/fphar.2021.708177