Cargando…

Basal Forebrain Cholinergic Neurons: Linking Down Syndrome and Alzheimer’s Disease

Down syndrome (DS, trisomy 21) is characterized by intellectual impairment at birth and Alzheimer’s disease (AD) pathology in middle age. As individuals with DS age, their cognitive functions decline as they develop AD pathology. The susceptibility to degeneration of a subset of neurons, known as ba...

Descripción completa

Detalles Bibliográficos
Autores principales: Martinez, Jose L., Zammit, Matthew D., West, Nicole R., Christian, Bradley T., Bhattacharyya, Anita
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8311593/
https://www.ncbi.nlm.nih.gov/pubmed/34322015
http://dx.doi.org/10.3389/fnagi.2021.703876