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Basal Forebrain Cholinergic Neurons: Linking Down Syndrome and Alzheimer’s Disease
Down syndrome (DS, trisomy 21) is characterized by intellectual impairment at birth and Alzheimer’s disease (AD) pathology in middle age. As individuals with DS age, their cognitive functions decline as they develop AD pathology. The susceptibility to degeneration of a subset of neurons, known as ba...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8311593/ https://www.ncbi.nlm.nih.gov/pubmed/34322015 http://dx.doi.org/10.3389/fnagi.2021.703876 |