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Binding of SARS-CoV-2 Fusion Peptide to Host Endosome and Plasma Membrane

[Image: see text] During infection the SARS-CoV-2 virus fuses its viral envelope with cellular membranes of its human host. The viral spike (S) protein mediates both the initial contact with the host cell and the subsequent membrane fusion. Proteolytic cleavage of S at the S2′ site exposes its fusio...

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Detalles Bibliográficos
Autores principales: Schaefer, Stefan L., Jung, Hendrik, Hummer, Gerhard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2021
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8311640/
https://www.ncbi.nlm.nih.gov/pubmed/34255499
http://dx.doi.org/10.1021/acs.jpcb.1c04176