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Mechanical Overloading Induced-Activation of mTOR Signaling in Tendon Stem/Progenitor Cells Contributes to Tendinopathy Development

Despite the importance of mechanical loading in tendon homeostasis and pathophysiology, the molecular responses involved in the mechanotransduction in tendon cells remain unclear. In this study, we found that in vitro mechanical loading activated the mammalian target of rapamycin (mTOR) in rat patel...

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Detalles Bibliográficos
Autores principales: Nie, Daibang, Zhou, Yiqin, Wang, Wang, Zhang, Jianying, Wang, James H.-C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8311934/
https://www.ncbi.nlm.nih.gov/pubmed/34322484
http://dx.doi.org/10.3389/fcell.2021.687856