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Mechanical Overloading Induced-Activation of mTOR Signaling in Tendon Stem/Progenitor Cells Contributes to Tendinopathy Development
Despite the importance of mechanical loading in tendon homeostasis and pathophysiology, the molecular responses involved in the mechanotransduction in tendon cells remain unclear. In this study, we found that in vitro mechanical loading activated the mammalian target of rapamycin (mTOR) in rat patel...
Autores principales: | Nie, Daibang, Zhou, Yiqin, Wang, Wang, Zhang, Jianying, Wang, James H.-C. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8311934/ https://www.ncbi.nlm.nih.gov/pubmed/34322484 http://dx.doi.org/10.3389/fcell.2021.687856 |
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