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Host Immune Responses after Suprachoroidal Delivery of AAV8 in Nonhuman Primate Eyes

The suprachoroid is a potential space located between the sclera and choroid of the eye, which provides a novel route for ocular drug or viral vector delivery. Suprachoroidal injection of adeno-associated virus (AAV)8 using transscleral microneedles enables widespread transgene expression in eyes of...

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Detalles Bibliográficos
Autores principales: Chung, Sook Hyun, Mollhoff, Iris Natalie, Mishra, Alaknanda, Sin, Tzu-Ni, Ngo, Taylor, Ciulla, Thomas, Sieving, Paul, Thomasy, Sara M., Yiu, Glenn
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Mary Ann Liebert, Inc., publishers 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8312020/
https://www.ncbi.nlm.nih.gov/pubmed/33446041
http://dx.doi.org/10.1089/hum.2020.281