Cargando…

Breast tumor stiffness instructs bone metastasis via maintenance of mechanical conditioning

While the immediate and transitory response of breast cancer cells to pathological stiffness in their native microenvironment has been well explored, it remains unclear how stiffness-induced phenotypes are maintained over time after cancer cell dissemination in vivo. Here, we show that fibrotic-like...

Descripción completa

Detalles Bibliográficos
Autores principales: Watson, Adam W., Grant, Adam D., Parker, Sara S., Hill, Samantha, Whalen, Michael B., Chakrabarti, Jayati, Harman, Michael W., Roman, Mackenzie R., Forte, Brittany L., Gowan, Cody C., Castro-Portuguez, Raúl, Stolze, Lindsey K., Franck, Christian, Cusanovich, Darren A., Zavros, Yana, Padi, Megha, Romanoski, Casey E., Mouneimne, Ghassan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8312405/
https://www.ncbi.nlm.nih.gov/pubmed/34192535
http://dx.doi.org/10.1016/j.celrep.2021.109293