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Aging-dependent loss of GAP junction proteins Cx46 and Cx50 in the fiber cells of human and mouse lenses accounts for the diminished coupling conductance

The homeostasis of the ocular lens is maintained by a microcirculation system propagated through gap junction channels. It is well established that the intercellular communications of the lens become deteriorative during aging. However, the molecular basis for this change in human lenses has not bee...

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Detalles Bibliográficos
Autores principales: Gong, Xiao-Dong, Wang, Yan, Hu, Xue-Bin, Zheng, Shu-Yu, Fu, Jia-Ling, Nie, Qian, Wang, Ling, Hou, Min, Xiang, Jia-Wen, Xiao, Yuan, Gao, Qian, Bai, Yue-Yue, Liu, Yi-Zhi, Li, David Wan-Cheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8312418/
https://www.ncbi.nlm.nih.gov/pubmed/34226295
http://dx.doi.org/10.18632/aging.203247