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Broad and Efficient Activation of Memory CD4(+) T Cells by Novel HAdV- and HCMV-Derived Peptide Pools

Reactivation of Human Cytomegalovirus (HCMV) and Human Adenovirus (HAdV) in immunocompromised patients following stem cell transplantation (SCT) or solid organ transplantation (SOT) is associated with high morbidity and mortality. The adoptive transfer of virus-specific CD8(+) and CD4(+) T cells has...

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Detalles Bibliográficos
Autores principales: Höttler, Alexander, März, Léo, Lübke, Maren, Rammensee, Hans-Georg, Stevanović, Stefan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8312486/
https://www.ncbi.nlm.nih.gov/pubmed/34322126
http://dx.doi.org/10.3389/fimmu.2021.700438