Aflibercept, a VEGF (Vascular Endothelial Growth Factor)-Trap, Reduces Vascular Permeability and Stroke-Induced Brain Swelling in Obese Mice

BACKGROUND AND PURPOSE: Brain edema is an important underlying pathology in acute stroke, especially when comorbidities are present. VEGF (Vascular endothelial growth factor) signaling is implicated in edema. This study investigated whether obesity impacts VEGF signaling and brain edema, as well as...

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Detalles Bibliográficos
Autores principales: Kim, Il-doo, Cave, John W., Cho, Sunghee
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2021
Materias:
Original Contributions
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8312568/
https://www.ncbi.nlm.nih.gov/pubmed/34192895
http://dx.doi.org/10.1161/STROKEAHA.121.034362

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8312568/
https://www.ncbi.nlm.nih.gov/pubmed/34192895
http://dx.doi.org/10.1161/STROKEAHA.121.034362

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