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Metabolic Traits and Stroke Risk in Individuals of African Ancestry: Mendelian Randomization Analysis

BACKGROUND AND PURPOSE: Metabolic traits affect ischemic stroke (IS) risk, but the degree to which this varies across different ethnic ancestries is not known. Our aim was to apply Mendelian randomization to investigate the causal effects of type 2 diabetes (T2D) liability and lipid traits on IS ris...

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Detalles Bibliográficos
Autores principales: Fatumo, Segun, Karhunen, Ville, Chikowore, Tinashe, Sounkou, Toure, Udosen, Brenda, Ezenwa, Chisom, Nakabuye, Mariam, Soremekun, Opeyemi, Daghlas, Iyas, Ryan, David K., Taylor, Amybel, Mason, Amy M., Damrauer, Scott M., Vujkovic, Marijana, Keene, Keith L., Fornage, Myriam, Järvelin, Marjo-Riitta, Burgess, Stephen, Gill, Dipender
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8312569/
https://www.ncbi.nlm.nih.gov/pubmed/34078102
http://dx.doi.org/10.1161/STROKEAHA.121.034747