NELL2-cdc42 signaling regulates BAF complexes and Ewing sarcoma cell growth

BAF chromatin remodeling complexes play important roles in chromatin regulation and cancer. Here, we report that Ewing sarcoma cells are dependent on the autocrine signaling mediated by NELL2, a secreted glycoprotein that has been characterized as an axon guidance molecule. NELL2 uses Robo3 as the r...

Descripción completa

Detalles Bibliográficos
Autores principales: Jayabal, Panneerselvam, Zhou, Fuchun, Lei, Xiufen, Ma, Xiuye, Blackman, Barron, Weintraub, Susan T., Houghton, Peter J., Shiio, Yuzuru
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8312579/
https://www.ncbi.nlm.nih.gov/pubmed/34233189
http://dx.doi.org/10.1016/j.celrep.2021.109254

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8312579/
https://www.ncbi.nlm.nih.gov/pubmed/34233189
http://dx.doi.org/10.1016/j.celrep.2021.109254

Ejemplares similares