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Baicalin Rescues Cognitive Dysfunction, Mitigates Neurodegeneration, and Exerts Anti-Epileptic Effects Through Activating TLR4/MYD88/Caspase-3 Pathway in Rats

PURPOSE: This study aims to evaluate the beneficial effects of anti-epileptic mechanisms of baicalin (BA) on cognitive dysfunction and neurodegeneration in pentylenetetrazol (PTZ)-induced epileptic rats. METHODS: First, PTZ-induced epileptic rats were administered intraperitoneally a sub-convulsive...

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Detalles Bibliográficos
Autores principales: Yang, Jiali, Jia, Zhixia, Xiao, Zhigang, Zhao, Jing, Lu, Ye, Chu, Li, Shao, Hui, Pei, Lin, Zhang, Shaodan, Chen, Yuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8312624/
https://www.ncbi.nlm.nih.gov/pubmed/34321866
http://dx.doi.org/10.2147/DDDT.S314076