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Thrombotic potential during pediatric acute lymphoblastic leukemia induction: Role of cell‐free DNA

BACKGROUND: Thromboembolism affects up to 30% of children undergoing treatment for acute lymphoblastic leukemia (ALL). Increased thrombin generation has been reported in ALL, but the mechanisms remain elusive. OBJECTIVE: We aimed to show that extracellular traps and cell‐free DNA (cfDNA) promote thr...

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Detalles Bibliográficos
Autores principales: Kumar, Rahul, Katare, Parmeshwar B., Lentz, Steven R., Modi, Arunkumar J., Sharathkumar, Anjali A., Dayal, Sanjana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8312738/
https://www.ncbi.nlm.nih.gov/pubmed/34337307
http://dx.doi.org/10.1002/rth2.12557