3: Multimodal Molecular Analysis Reveals Divergent Trajectories Of Wound Regeneration Versus Fibrosis

PURPOSE: Scarring in the mouse dorsal dermis is mediated by pro-fibrotic, Engrailed-1 lineage-positive fibroblasts (EPFs). We recently showed that mechanotransduction blockade (YAP inhibition, using the drug verteporfin), results in complete wound regeneration, with full recovery of normal dermal ap...

Descripción completa

Detalles Bibliográficos
Autores principales: desJardins-Park, Heather E., Mascharak, Shamik, Januszyk, Michael, Chen, Kellen, Davitt, Michael F., Demeter, Janos, Henn, Dominic, Griffin, Michelle, Bonham, Clark A., Mooney, Nancie, Cheng, Ran, Jackson, Peter K., Wan, Derrick C., Gurtner, Geoffrey C., Longaker, Michael T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2021
Materias:
PSRC 2021 Abstract Supplement
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8312805/
http://dx.doi.org/10.1097/01.GOX.0000769936.79898.fc

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8312805/
http://dx.doi.org/10.1097/01.GOX.0000769936.79898.fc

Ejemplares similares