Tree Shrew Cells Transduced with Human CD4 and CCR5 Support Early Steps of HIV-1 Replication, but Viral Infectivity Is Restricted by APOBEC3

The host range of human immunodeficiency virus type 1 (HIV-1) is narrow. Therefore, using ordinary animal models to study HIV-1 replication, pathogenesis, and therapy is impractical. The lack of applicable animal models for HIV-1 research spurred our investigation on whether tree shrews (Tupaia bela...

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Detalles Bibliográficos
Autores principales: Luo, Meng-Ting, Mu, Dan, Yang, Xiang, Luo, Rong-Hua, Zheng, Hong-Yi, Chen, Min, Guo, Ying-Qi, Zheng, Yong-Tang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2021
Materias:
Virus-Cell Interactions
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8312864/
https://www.ncbi.nlm.nih.gov/pubmed/34076481
http://dx.doi.org/10.1128/JVI.00020-21

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8312864/
https://www.ncbi.nlm.nih.gov/pubmed/34076481
http://dx.doi.org/10.1128/JVI.00020-21

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