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Pch2 orchestrates the meiotic recombination checkpoint from the cytoplasm

During meiosis, defects in critical events trigger checkpoint activation and restrict cell cycle progression. The budding yeast Pch2 AAA+ ATPase orchestrates the checkpoint response launched by synapsis deficiency; deletion of PCH2 or mutation of the ATPase catalytic sites suppress the meiotic block...

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Detalles Bibliográficos
Autores principales: Herruzo, Esther, Lago-Maciel, Ana, Baztán, Sara, Santos, Beatriz, Carballo, Jesús A., San-Segundo, Pedro A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8312941/
https://www.ncbi.nlm.nih.gov/pubmed/34260586
http://dx.doi.org/10.1371/journal.pgen.1009560