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Defining the Glycosaminoglycan Interactions of Complement Factor H–Related Protein 5
Complement activation is an important mediator of kidney injury in glomerulonephritis. Complement factor H (FH) and FH-related protein 5 (FHR-5) influence complement activation in C3 glomerulopathy and IgA nephropathy by differentially regulating glomerular complement. FH is a negative regulator of...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
AAI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8313009/ https://www.ncbi.nlm.nih.gov/pubmed/34193601 http://dx.doi.org/10.4049/jimmunol.2000072 |