CYP2B6 Functional Variability in Drug Metabolism and Exposure Across Populations—Implication for Drug Safety, Dosing, and Individualized Therapy

Adverse drug reactions (ADRs) are one of the major causes of morbidity and mortality worldwide. It is well-known that individual genetic make-up is one of the causative factors of ADRs. Approximately 14 million single nucleotide polymorphisms (SNPs) are distributed throughout the entire human genome...

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Detalles Bibliográficos
Autores principales: Langmia, Immaculate M., Just, Katja S., Yamoune, Sabrina, Brockmöller, Jürgen, Masimirembwa, Collen, Stingl, Julia C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Genetics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8313315/
https://www.ncbi.nlm.nih.gov/pubmed/34322158
http://dx.doi.org/10.3389/fgene.2021.692234

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8313315/
https://www.ncbi.nlm.nih.gov/pubmed/34322158
http://dx.doi.org/10.3389/fgene.2021.692234

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