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A Review on Expression, Pathological Roles, and Inhibition of TMPRSS2, the Serine Protease Responsible for SARS-CoV-2 Spike Protein Activation

SARS-CoV-2, the coronavirus responsible for the COVID-19 pandemic, uses the host cell membrane receptor angiotensin-converting enzyme 2 (ACE2) for anchoring its spike protein, and the subsequent membrane fusion process is facilitated by host membrane proteases. Recent studies have shown that transme...

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Detalles Bibliográficos
Autores principales: Sarker, Jyotirmoy, Das, Pritha, Sarker, Sabarni, Roy, Apurba Kumar, Momen, A. Z. M. Ruhul
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8313365/
https://www.ncbi.nlm.nih.gov/pubmed/34336361
http://dx.doi.org/10.1155/2021/2706789