Multiple sclerosis is linked to MAPK(ERK) overactivity in microglia

Reassessment of published observations in patients with multiple sclerosis (MS) suggests a microglial malfunction due to inappropriate (over)activity of the mitogen-activated protein kinase pathway ERK (MAPK(ERK)). These observations regard biochemistry as well as epigenetics, and all indicate invol...

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Detalles Bibliográficos
Autores principales: ten Bosch, George J. A., Bolk, Jolande, ‘t Hart, Bert A., Laman, Jon D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2021
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8313465/
https://www.ncbi.nlm.nih.gov/pubmed/33948692
http://dx.doi.org/10.1007/s00109-021-02080-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8313465/
https://www.ncbi.nlm.nih.gov/pubmed/33948692
http://dx.doi.org/10.1007/s00109-021-02080-4

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