SENP1 promotes MCL pathogenesis through regulating JAK-STAT5 pathway and SOCS2 expression

Mantle cell lymphoma (MCL) is highly aggressive and its treatment remains challenging, understanding its pathogenesis is critical for future targeted therapy. SUMO specific proteases 1 (SENP1) is an important protein that regulates the balance between SUMOylation and deSUMOylation. We found that SEN...

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Detalles Bibliográficos
Autores principales: Zhang, Yali, Ma, Yanni, Wu, Guixian, Xie, Mingling, Luo, Chengxin, Huang, Xiangtao, Tian, Feng, Chen, Jieping, Li, Xi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8313533/
https://www.ncbi.nlm.nih.gov/pubmed/34312374
http://dx.doi.org/10.1038/s41420-021-00578-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8313533/
https://www.ncbi.nlm.nih.gov/pubmed/34312374
http://dx.doi.org/10.1038/s41420-021-00578-x

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