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SENP1 promotes MCL pathogenesis through regulating JAK-STAT5 pathway and SOCS2 expression
Mantle cell lymphoma (MCL) is highly aggressive and its treatment remains challenging, understanding its pathogenesis is critical for future targeted therapy. SUMO specific proteases 1 (SENP1) is an important protein that regulates the balance between SUMOylation and deSUMOylation. We found that SEN...
Autores principales: | Zhang, Yali, Ma, Yanni, Wu, Guixian, Xie, Mingling, Luo, Chengxin, Huang, Xiangtao, Tian, Feng, Chen, Jieping, Li, Xi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8313533/ https://www.ncbi.nlm.nih.gov/pubmed/34312374 http://dx.doi.org/10.1038/s41420-021-00578-x |
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