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Dopamine-loaded nanoparticle systems circumvent the blood–brain barrier restoring motor function in mouse model for Parkinson’s Disease

Parkinson's disease (PD) is a progressive and chronic neurodegenerative disease of the central nervous system. Early treatment for PD is efficient; however, long-term systemic medication commonly leads to deleterious side-effects. Strategies that enable more selective drug delivery to the brain...

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Detalles Bibliográficos
Autores principales: Monge-Fuentes, Victoria, Biolchi Mayer , Andréia, Lima, Marcos Robalinho, Geraldes, Luiza Ribeiro, Zanotto, Larissa Nepomuceno, Moreira, Karla Graziella, Martins, Olimpia Paschoal, Piva, Henrique Luís, Felipe, Maria Sueli Soares, Amaral, Andre Correa, Bocca, Anamélia Lorenzetti, Tedesco, Antonio Claudio, Mortari, Márcia Renata
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8313547/
https://www.ncbi.nlm.nih.gov/pubmed/34312413
http://dx.doi.org/10.1038/s41598-021-94175-8