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Dopamine-loaded nanoparticle systems circumvent the blood–brain barrier restoring motor function in mouse model for Parkinson’s Disease
Parkinson's disease (PD) is a progressive and chronic neurodegenerative disease of the central nervous system. Early treatment for PD is efficient; however, long-term systemic medication commonly leads to deleterious side-effects. Strategies that enable more selective drug delivery to the brain...
Autores principales: | Monge-Fuentes, Victoria, Biolchi Mayer , Andréia, Lima, Marcos Robalinho, Geraldes, Luiza Ribeiro, Zanotto, Larissa Nepomuceno, Moreira, Karla Graziella, Martins, Olimpia Paschoal, Piva, Henrique Luís, Felipe, Maria Sueli Soares, Amaral, Andre Correa, Bocca, Anamélia Lorenzetti, Tedesco, Antonio Claudio, Mortari, Márcia Renata |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8313547/ https://www.ncbi.nlm.nih.gov/pubmed/34312413 http://dx.doi.org/10.1038/s41598-021-94175-8 |
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