Nuclear iASPP determines cell fate by selectively inhibiting either p53 or NF-κB

p53 and NF-κBp65 are essential transcription factors (TFs) in the cellular response to stress. Two signaling systems can often be entwined together and generally produce opposing biological outcomes in a cell context-dependent manner. Inhibitor of apoptosis-stimulating protein of p53 (iASPP) has the...

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Detalles Bibliográficos
Autores principales: Ge, Wenjie, Wang, Yudong, Zheng, Shanliang, Zhao, Dong, Wang, Xingwen, Zhang, Xiaoshi, Hu, Ying
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8313550/
https://www.ncbi.nlm.nih.gov/pubmed/34312379
http://dx.doi.org/10.1038/s41420-021-00582-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8313550/
https://www.ncbi.nlm.nih.gov/pubmed/34312379
http://dx.doi.org/10.1038/s41420-021-00582-1

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