S494 O-glycosylation site on the SARS-CoV-2 RBD affects the virus affinity to ACE2 and its infectivity; a molecular dynamics study

SARS-CoV-2 is a strain of Coronavirus family that caused the ongoing pandemic of COVID-19. Several studies showed that the glycosylation of virus spike (S) protein and the Angiotensin-Converting Enzyme 2 (ACE2) receptor on the host cell is critical for the virus infectivity. Molecular Dynamics (MD)...

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Detalles Bibliográficos
Autores principales: Rahnama, Shadi, Azimzadeh Irani, Maryam, Amininasab, Mehriar, Ejtehadi, Mohammad Reza
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8313699/
https://www.ncbi.nlm.nih.gov/pubmed/34312429
http://dx.doi.org/10.1038/s41598-021-94602-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8313699/
https://www.ncbi.nlm.nih.gov/pubmed/34312429
http://dx.doi.org/10.1038/s41598-021-94602-w

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