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KBP-066A, a long-acting dual amylin and calcitonin receptor agonist, induces weight loss and improves glycemic control in obese and diabetic rats

OBJECTIVE: Dual amylin and calcitonin receptor agonists (DACRAs) are novel therapeutic agents that not only improve insulin sensitivity but also work as an adjunct to established T2DM therapies. DACRAs are currently administered once daily, though it is unknown whether DACRAs with increased plasma h...

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Detalles Bibliográficos
Autores principales: Andreassen, K.V., Larsen, A.T., Sonne, N., Mohamed, K.E., Karsdal, M.A., Henriksen, K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8313742/
https://www.ncbi.nlm.nih.gov/pubmed/34214708
http://dx.doi.org/10.1016/j.molmet.2021.101282