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Integrating readout of somatic mutations in individual cells with single-cell transcriptional profiling

In many biological applications, the readout of somatic mutations in individual cells is essential. For example, it can be used to mark individual cancer cells or identify progenies of a stem cell. Here, we present a protocol to perform single-cell RNA-seq and single-cell amplicon-seq using 10X Chro...

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Detalles Bibliográficos
Autores principales: Liu, Shichen, Nguyen, Maximilian, Hormoz, Sahand
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8313752/
https://www.ncbi.nlm.nih.gov/pubmed/34337442
http://dx.doi.org/10.1016/j.xpro.2021.100673