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Integrating readout of somatic mutations in individual cells with single-cell transcriptional profiling
In many biological applications, the readout of somatic mutations in individual cells is essential. For example, it can be used to mark individual cancer cells or identify progenies of a stem cell. Here, we present a protocol to perform single-cell RNA-seq and single-cell amplicon-seq using 10X Chro...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8313752/ https://www.ncbi.nlm.nih.gov/pubmed/34337442 http://dx.doi.org/10.1016/j.xpro.2021.100673 |