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Priming mycobacterial ESX-secreted protein B to form a channel-like structure

ESX-1 is a major virulence factor of Mycobacterium tuberculosis, a secretion machinery directly involved in the survival of the microorganism from the immune system defence. It disrupts the phagosome membrane of the host cell through a contact-dependent mechanism. Recently, the structure of the inne...

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Detalles Bibliográficos
Autores principales: Gijsbers, Abril, Vinciauskaite, Vanesa, Siroy, Axel, Gao, Ye, Tria, Giancarlo, Mathew, Anjusha, Sánchez-Puig, Nuria, López-Iglesias, Carmen, Peters, Peter J., Ravelli, Raimond B.G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8313811/
https://www.ncbi.nlm.nih.gov/pubmed/34337436
http://dx.doi.org/10.1016/j.crstbi.2021.06.001