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Negative Feedback Role of Astrocytes in Shaping Excitation in Brain Cell Co-cultures

Glial cells play an important role in maintaining neuronal homeostasis and may thus influence excitability in epileptogenesis. These cells in the brain have glutamate (Glu) transporters, which remove this neurotransmitter from the extracellular space. Lack of negative (−) feedback makes local neuron...

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Detalles Bibliográficos
Autores principales: Khezerlou, Elnaz, Prajapati, Neela, DeCoster, Mark A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8313828/
https://www.ncbi.nlm.nih.gov/pubmed/34326721
http://dx.doi.org/10.3389/fncel.2021.651509