Effects of blocking chemokine receptor CCR1 with BX471 in two models of fibrosis prevention and rescue in mice

BACKGROUND: The induction, progression and resolution of liver fibrosis are influenced by multiple chemokines. The inhibition of CCR1 signalling by a specific non-peptide inhibitor (BX471) reduces kidney fibrosis after unilateral ureteral obstruction via suppression of leukocyte recruitment in mice....

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Detalles Bibliográficos
Autores principales: Weber, Susanne N., Nowak, Irina, Grünhage, Frank, Lammert, Frank
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8313839/
https://www.ncbi.nlm.nih.gov/pubmed/34337167
http://dx.doi.org/10.1016/j.bbrep.2021.101077

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8313839/
https://www.ncbi.nlm.nih.gov/pubmed/34337167
http://dx.doi.org/10.1016/j.bbrep.2021.101077

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