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Effects of blocking chemokine receptor CCR1 with BX471 in two models of fibrosis prevention and rescue in mice
BACKGROUND: The induction, progression and resolution of liver fibrosis are influenced by multiple chemokines. The inhibition of CCR1 signalling by a specific non-peptide inhibitor (BX471) reduces kidney fibrosis after unilateral ureteral obstruction via suppression of leukocyte recruitment in mice....
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Elsevier
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8313839/ https://www.ncbi.nlm.nih.gov/pubmed/34337167 http://dx.doi.org/10.1016/j.bbrep.2021.101077 |