Interneuron Heterotopia in the Lis1 Mutant Mouse Cortex Underlies a Structural and Functional Schizophrenia-Like Phenotype

LIS1 is one of the principal genes related to Type I lissencephaly, a severe human brain malformation characterized by an abnormal neuronal migration in the cortex during embryonic development. This is clinically associated with epilepsy and cerebral palsy in severe cases, as well as a predispositio...

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Detalles Bibliográficos
Autores principales: Garcia-Lopez, Raquel, Pombero, Ana, Estirado, Alicia, Geijo-Barrientos, Emilio, Martinez, Salvador
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Cell and Developmental Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8313859/
https://www.ncbi.nlm.nih.gov/pubmed/34327202
http://dx.doi.org/10.3389/fcell.2021.693919

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8313859/
https://www.ncbi.nlm.nih.gov/pubmed/34327202
http://dx.doi.org/10.3389/fcell.2021.693919

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