Cargando…

An optogenetic method for interrogating YAP1 and TAZ nuclear–cytoplasmic shuttling

The shuttling of transcription factors and transcriptional regulators into and out of the nucleus is central to the regulation of many biological processes. Here we describe a new method for studying the rates of nuclear entry and exit of transcriptional regulators. A photo-responsive LOV (light–oxy...

Descripción completa

Detalles Bibliográficos
Autores principales: Dowbaj, Anna M., Jenkins, Robert P., Williamson, Daniel, Heddleston, John M., Ciccarelli, Alessandro, Fallesen, Todd, Hahn, Klaus M., O'Dea, Reuben D., King, John R., Montagner, Marco, Sahai, Erik
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8313864/
https://www.ncbi.nlm.nih.gov/pubmed/34060624
http://dx.doi.org/10.1242/jcs.253484