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Chemical approaches to discover the full potential of peptide nucleic acids in biomedical applications

Peptide nucleic acid (PNA) is arguably one of the most successful DNA mimics, despite a most dramatic departure from the native structure of DNA. The present review summarizes 30 years of research on PNA’s chemistry, optimization of structure and function, applications as probes and diagnostics, and...

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Detalles Bibliográficos
Autores principales: Brodyagin, Nikita, Katkevics, Martins, Kotikam, Venubabu, Ryan, Christopher A, Rozners, Eriks
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Beilstein-Institut 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8313981/
https://www.ncbi.nlm.nih.gov/pubmed/34367346
http://dx.doi.org/10.3762/bjoc.17.116