Suppressing ERK Pathway Impairs Glycochenodeoxycholate-Mediated Survival and Drug-Resistance in Hepatocellular Carcinoma Cells

Glycochenodeoxycholate (GCDA), a toxic component in bile salts, is involved in carcinogenesis of gastrointestinal tumors. The objective of this research was to study the function of ERK1/2 in the GCDA-mediated survival and drug-resistance in hepatocellular carcinoma cells (HCCs). Firstly, extracellu...

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Detalles Bibliográficos
Autores principales: Li, Bingxin, Zhou, Maojun, Wang, Jue, Xu, Hongjuan, Yang, Manyi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Oncology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8313996/
https://www.ncbi.nlm.nih.gov/pubmed/34327135
http://dx.doi.org/10.3389/fonc.2021.663944

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8313996/
https://www.ncbi.nlm.nih.gov/pubmed/34327135
http://dx.doi.org/10.3389/fonc.2021.663944

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