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PSGL-1 Is a T Cell Intrinsic Inhibitor That Regulates Effector and Memory Differentiation and Responses During Viral Infection

Effective T cell differentiation during acute virus infections leads to the generation of effector T cells that mediate viral clearance, as well as memory T cells that confer protection against subsequent reinfection. While inhibitory immune checkpoints have been shown to promote T cell dysfunction...

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Detalles Bibliográficos
Autores principales: Tinoco, Roberto, Neubert, Emily N., Stairiker, Christopher J., Henriquez, Monique L., Bradley, Linda M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8314012/
https://www.ncbi.nlm.nih.gov/pubmed/34326837
http://dx.doi.org/10.3389/fimmu.2021.677824