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Overexpression of Cancer-Associated Stem Cell Gene OLFM4 in the Colonic Epithelium of Patients With Primary Sclerosing Cholangitis

BACKGROUND: To examine immune-epithelial interactions and their impact on epithelial transformation in primary sclerosing cholangitis–associated ulcerative colitis (PSC-UC) using patient-derived colonic epithelial organoid cultures (EpOCs). METHODS: The EpOCs were originated from colonic biopsies fr...

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Detalles Bibliográficos
Autores principales: Neyazi, Mastura, Bharadwaj, Sraddha S, Bullers, Samuel, Varenyiova, Zofia, Travis, Simon, Arancibia-Cárcamo, Carolina V, Powrie, Fiona, Geremia, Alessandra
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8314119/
https://www.ncbi.nlm.nih.gov/pubmed/33570127
http://dx.doi.org/10.1093/ibd/izab025