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Pharmacokinetics, Urinary Excretion, and Pharmaco-Metabolomic Study of Tebipenem Pivoxil Granules After Single Escalating Oral Dose in Healthy Chinese Volunteers

Tebipenem pivoxil (TBPM-PI), an oral carbapenem antibiotic, has shown special advantages in pediatric infections and was in urgent need in China. Although pharmacokinetics, urinary excretion, and metabolite information of its active form tebipenem (TBPM) has been reported, ethnic differences may exi...

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Detalles Bibliográficos
Autores principales: Li, Zeyun, Su, Mei, Cheng, Weiyan, Xia, Jueyu, Liu, Shuaibing, Liu, Ruijuan, Sun, Suke, Feng, Luyao, Zhu, Xueya, Zhang, Xiaojian, Tian, Xin, Qu, Lingbo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8314177/
https://www.ncbi.nlm.nih.gov/pubmed/34326771
http://dx.doi.org/10.3389/fphar.2021.696165