Cargando…

Pharmacokinetics, Urinary Excretion, and Pharmaco-Metabolomic Study of Tebipenem Pivoxil Granules After Single Escalating Oral Dose in Healthy Chinese Volunteers

Tebipenem pivoxil (TBPM-PI), an oral carbapenem antibiotic, has shown special advantages in pediatric infections and was in urgent need in China. Although pharmacokinetics, urinary excretion, and metabolite information of its active form tebipenem (TBPM) has been reported, ethnic differences may exi...

Descripción completa

Detalles Bibliográficos
Autores principales:	Li, Zeyun, Su, Mei, Cheng, Weiyan, Xia, Jueyu, Liu, Shuaibing, Liu, Ruijuan, Sun, Suke, Feng, Luyao, Zhu, Xueya, Zhang, Xiaojian, Tian, Xin, Qu, Lingbo
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2021
Materias:	Pharmacology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8314177/ https://www.ncbi.nlm.nih.gov/pubmed/34326771 http://dx.doi.org/10.3389/fphar.2021.696165

Ejemplares similares

Crystal structure of tebipenem pivoxil
por: Tang, Chao, et al.
Publicado: (2018)

1105. Population Pharmacokinetic Analyses for Tebipenem After the Administration of Tebipenem Pivoxil Hydrobromide
por: Ganesan, Harish, et al.
Publicado: (2021)

Population Pharmacokinetic Analyses for Tebipenem after Oral Administration of Pro-Drug Tebipenem Pivoxil Hydrobromide
por: Ganesan, H., et al.
Publicado: (2023)

Absorption, Metabolism, and Excretion of [(14)C]-Tebipenem Pivoxil Hydrobromide (TBP-PI-HBr) in Healthy Male Subjects
por: Gupta, Vipul K., et al.
Publicado: (2023)

Bioequivalence of two oral formulations of tebipenem pivoxil hydrobromide in healthy subjects
por: Gupta, Vipul K., et al.
Publicado: (2022)

Investigation of pneumonia-causing pathogenic organisms in children and the usefulness of tebipenem pivoxil for their treatment
por: Kuroki, Haruo, et al.
Publicado: (2010)

Pharmacokinetics of Oral Tebipenem Pivoxil Hydrobromide in Subjects with Various Degrees of Renal Impairment
por: Patel, Gina, et al.
Publicado: (2022)

Cyclodextrins as multifunctional excipients: Influence of inclusion into β-cyclodextrin on physicochemical and biological properties of tebipenem pivoxil
por: Paczkowska, Magdalena, et al.
Publicado: (2019)

1120. Absorption, Metabolism, and Excretion of [(14)C]-Tebipenem Pivoxil Hydrobromide (TBP-PI-HBr) Following a Single Oral Dose in Healthy Male Subjects
por: Gupta, Vipul K, et al.
Publicado: (2021)

The repurposing of Tebipenem pivoxil as alternative therapy for severe gastrointestinal infections caused by extensively drug-resistant Shigella spp
por: Fernández Álvaro, Elena, et al.
Publicado: (2022)

1095. Pharmacokinetics-Pharmacodynamics Evaluation of Tebipenem Pivoxil Hydrobromide Using the 10-Day Hollow-Fiber In Vitro Infection Model
por: VanScoy, Brian D, et al.
Publicado: (2021)

Correction: The repurposing of Tebipenem pivoxil as alternative therapy for severe gastrointestinal infections caused by extensively drug-resistant Shigella spp
por: Fernández Álvaro, Elena, et al.
Publicado: (2022)

Safety, Pharmacokinetics, and Food Effect of Tebipenem Pivoxil Hydrobromide after Single and Multiple Ascending Oral Doses in Healthy Adult Subjects
por: Eckburg, Paul B., et al.
Publicado: (2019)

1304. Characterization of Tebipenem Pivoxil Hydrobromide Pharmacokinetics-Pharmacodynamics (PK-PD) in a Neutropenic Murine Acute Pyelonephritis (AP) Model
por: VanScoy, Brian D, et al.
Publicado: (2020)

Antibacterial Properties of Tebipenem Pivoxil Tablet, a New Oral Carbapenem Preparation against a Variety of Pathogenic Bacteria in Vitro and in Vivo
por: Yao, Qi, et al.
Publicado: (2016)

Randomized, Double-Blind, Placebo- and Positive-Controlled Crossover Study of the Effects of Tebipenem Pivoxil Hydrobromide on QT/QTc Intervals in Healthy Subjects
por: Gupta, Vipul K., et al.
Publicado: (2021)

1122. Effect of Aluminum Hydroxide/Magnesium Hydroxide/Simethicone and Omeprazole on the Pharmacokinetics of Tebipenem Pivoxil Hydrobromide (TBP-PI-HBr) in Healthy Adult Subjects
por: Gupta, Vipul K, et al.
Publicado: (2021)

Effect of an Antacid (Aluminum Hydroxide/Magnesium Hydroxide/Simethicone) or a Proton Pump Inhibitor (Omeprazole) on the Pharmacokinetics of Tebipenem Pivoxil Hydrobromide (TBP-PI-HBr) in Healthy Adult Subjects
por: Patel, Gina, et al.
Publicado: (2023)

LB-3. Oral Tebipenem Pivoxil Hydrobromide is Non-inferior to IV Ertapenem in Complicated Urinary Tract Infection (cUTI) and Acute Pyelonephritis (AP) – Results from the Pivotal ADAPT-PO Study
por: Muir, Lori A, et al.
Publicado: (2020)

A Single Dose of Baicalin Has No Clinically Significant Effect on the Pharmacokinetics of Cyclosporine A in Healthy Chinese Volunteers
por: Liu, Ruijuan, et al.
Publicado: (2019)

PharmacoSTORM nanoscale pharmacology reveals cariprazine binding on Islands of Calleja granule cells
por: Prokop, Susanne, et al.
Publicado: (2021)

Cefditoren pivoxil associated rash and arthralgia in a child
por: Nandy, Manab, et al.
Publicado: (2012)

Stability-Indicating HPLC Method for the Determination of Cefcapene Pivoxil
por: Zalewski, Przemysław, et al.
Publicado: (2012)

Pharmaco-prosthodontics revisited
por: Jagadeeshwaran, A. R., et al.
Publicado: (2012)

Tebipenem as an oral alternative for the treatment of typhoid caused by XDR Salmonella Typhi
por: Mylona, Elli, et al.
Publicado: (2021)

Spectrophotometric Determination of Cefetamet Pivoxil Hydrochloride and Pitavastatin Calcium in Tablet Dosage form
por: Vadia, N. H., et al.
Publicado: (2008)

Development and validation of the stability-indicating LC–UV method for the determination of Cefditoren pivoxil
por: Annapurna, M. Mathrusri, et al.
Publicado: (2012)

Relapsing Hypoglycemia Associated with Hypocarnitinemia Following Treatment with Cefcapene Pivoxil in an Elderly Man
por: Hanai, Shogo, et al.
Publicado: (2019)

PHARMACO – THERAPEUTICS OF DASEMANI DRUGS
por: Sircar, N. N.
Publicado: (1984)

ArrhythmoGenoPharmacoTherapy
por: Tosaki, Arpad
Publicado: (2020)

Absorption, metabolism and excretion of opicapone in human healthy volunteers
por: Loureiro, Ana I., et al.
Publicado: (2022)

Stress Degradation Studies of Tebipenem and a Validated Stability-Indicating LC Method
por: Cielecka-Piontek, Judyta, et al.
Publicado: (2012)

From pharmaco-therapy to pharmaco-prevention: trends in prescribing to older adults in Ontario, Canada, 1997-2006
por: Bajcar, Jana M, et al.
Publicado: (2010)

Botulinum toxin as treatment for focal dystonia: a systematic review of the pharmaco-therapeutic and pharmaco-economic value
por: Zoons, E., et al.
Publicado: (2012)

Formulation development and rheological studies of palatable cefetamet pivoxil hydrochloride dry powder suspension
por: Sateesha, SB., et al.
Publicado: (2011)

EFFICACY AND TOLERABILITY OF CEFDITOREN PIVOXIL IN UNCOMPLICATED SKIN AND SKIN STRUCTURE INFECTIONS IN INDIAN PATIENTS
por: Manaktala, Charu, et al.
Publicado: (2009)

Preparation and characterization of cefditoren pivoxil-loaded liposomes for controlled in vitro and in vivo drug release
por: Venugopalarao, Gojjala, et al.
Publicado: (2015)

Facilitated/Pharmaco-invasive Approaches in STEMI
por: Capodanno, Davide, et al.
Publicado: (2012)

Epigenetics and pharmaco-epigenetics in the primary headaches
por: Montagna, Pasquale
Publicado: (2008)

Pharmaco-Immunomodulatory Therapy in COVID-19
por: Rizk, John G., et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_2ji309cfliqrik039pcghbddkh